Rodica E. Ionescu
University of Technology of Troyes, France
Title: Ultrasenstive Biodetection of Worldwide Pathogens: From Classical Methods to Advanced Biosensing Technologies
Biography
Biography: Rodica E. Ionescu
Abstract
Recently, the world is experiencing with dramatic climatic changes, which have led either to the emergence or to the amplification of new pathogenic agents (bacteria and viruses for example). The most significant example is the appearance of the SARS-COvid-2019 virus which greatly slowed down various human activities at the beginning of 2020 due to several confinements which have followed one another in a wave of "stop and go" for more than two years in different areas of the globe. Therefore, many multidisciplinary research teams and private companies have been deeply involved in the development of rapid, portable and unique modern bioassays medical devices that greatly help the doctors/pharmacists/nurses to monitor the presence/absence of COvid virus. In this context, classical biotechnological methods such as polymerase chain reaction and radiological investigations have also been widely used despite their high prices, long procedures and long-term trained personnel. Moreover, the sensitivity and specificity of the assays based on lateral flow principles were many times questionable due to ineffective visibility to the human eye of colorimetric false/positive gold lines formed in the presence of very low COvid virus loads. Therefore, modern biosensing prototypes are needed to correlate virus/antibody concentration with CoVid infection status and occurrence of specific biomarkers, namely viral proteins in body fluids (nasal mucosa, saliva, blood, urine, etc). This conference focuses on recent disposable devices for biodetection of the COvid virus and its associated viral mutations. In addition, the biosensing of gliadins food allergens and Brettanomyces bruxellesis wine pathogens on miniaturized solid supports will also be addressed